Nicotinamide Side Effects


Nicotinamide is a form of Vitamin B3 that also goes by the name niacinamide. It is water soluble and one of the most popular Vitamin commercially produced . The annual production of Nicotinamide runs into thousands of tons which indicate just how popular its usage is.

This form of Vitamin B3 is used in the treatment of a number of health conditions. Among the conditions Nicotinamide is used to treat include Acne Vulgaris. It is popularly used to treat niacin deficiency as well as prevention of the condition. It also treats Acne Vulgaris by making use of its anti-inflammatory side effects. Clinical trials have been conducted on the possibility of using it in the treatment of skin cancer and anxiety.

The wide use of this compound points to its safe-to-use reputation. It is generally considered safe to consume, as long as the consumption does not exceed 3 gram per day in adults, after which it becomes toxic.

Even when consumed in moderation, there are some side effects that consumers are bound to experience with time. Herein are some of its side effects that are common and widespread.


Direct Nicotinamide Side Effects

Consuming Nicotinamide may cause episodes of dizziness, nausea, stomach upset and body temperature flushes. One may also experience migraines, diarrhea, and itching skin. These side effects elapse after a short while and are considered mild. In many instances, they dissipate on their own without a need for medication.

Other possible side effects that might necessitate medical attention include chest tightening, muscle aches blurry vision and mouth, lips, or tongue swelling. Prudence dictates that you seek medical attention when the mild side effects above persist over a long period.

Severe Side Effects

Severe side effects are commonly experienced when there is a misuse of Nicotinamide involved. A misuse occurs when one consumes more than 3 grams of Nicotinamide per day.

One very severe side effect of excessive consumption of this substance is liver problems. Liver problems also have a knock on effect such as yellowing of the skin. Abdominally fast heartbeats and excessive vomiting are other severe side effects that have been experienced due to abuse of Nicotinamide. Beyond vomiting, another stomach problem that may arise as a side effect is the development of ulcers.

While consuming this substance you should also be aware of one side effect that could have devastating effects on your health. Prolonged and excessive consumption of this substance causes high blood sugar, which can cause diabetes or exacerbate it.

Indirect Side Effects

One of the common indirect side effect of taking Nicotinamide results from interaction with other substances in the body (especially in the stomach). When Nicotinamide is taken along with alcoholic substances, it may cause lactic acidosis and delirium. Lactic acidosis is characterized by an abnormal buildup of lactic acid in the body tissues while delirium is characterized by a decline cognitive function.

There is also the possibility of experiencing weakness when Nicotinamide is taken along with a class of drugs called fibrates.

Before consuming Nicotinamide always consult a doctor. If only for your health, a trip to the doctor’s office for some professional opinion before consuming Nicotinamide is worth it.

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